More About Liver Disease
Prior to the pandemic, according to the CDC, roughly 4.5 million American men and women were diagnosed with chronic liver disease or cirrhosis in the year 2018 alone. During the same year there were a recorded 44,358 related mortalities. Despite the fact that liver disease typically takes years to develop, young women who drink excessively are likely to develop the condition more quickly. This is, in large part, because their bodies process alcohol differently than men’s. An article published by the US National Library of Medicine says that alcoholic liver disease progresses more rapidly in women for a number of reasons.
“Experiments in rats suggest that higher endotoxin levels and increased gut permeability to endotoxin likely contribute to more severe liver injury in females,” the article states. “Estrogen receptor concentrations within the liver differ between the sexes, and estrogen appears to activate liver Kupffer cells. This results in increased inflammation and necrosis, which can be counteracted by treating female rats with an antiestrogen. Alcohol also may induce differential expression of genes in rats, leading to increased oxidative stress, inflammation, and injury in female rats.”
There is ample evidence supporting the fact that women are more likely to suffer consequences related to excessive alcohol consumption earlier on in life than their male counterparts.